Endocrine Abstracts

Neonatal autoimmune hyperthyroidism is rare but potentially fatal condition. It occurs in 1-5% of infants born to pregnant mothers with Graves’ disease (GD). We present a case of transient neonatal thyrotoxicosis born to pregnant women with GD and high TSH Receptor antibodies. 42 years pregnant lady was referred to Antenatal Endocrine clinic at Walsall Manor Hospital in 15th week of pregnancy with symptoms of Thyrotoxicosis. She has GD and was taking Propylthio...

62 year-old lady with a long history of hypokalaemia, hypertension and a random aldosterone of 786 pmol/l with suppressed renin of <8.0 mU/l at a time when she was taking Nebivolol, perindopril and Felodipine. Her Hypokalaemia improved after addition of Spironolactone and remained above 3.5 mmol/l. Biochemical work up confirmed a diagnosis of Conn’s syndrome and her BP control improved after addition of Aldosterone antagonist as above. Adrenal MRI revealed a 13 mm adr...

Introduction: Diabetes Ketoacidosis, DKA, is a serious condition with significant morbidity and mortality. Most DKA patients are potassium deficient, but present with hyperkalaemia due to severe acidosis and insulin deficiency. Hypokalaemia at presentation of DKA is extremely uncommon.Clinical case: A 25 year old man was admitted with severe DKA as a first presentation of diabetes. His venous pH was 6.97, bicarbonate 3.0 mmol/l, potassium 3.4 mmol/l. He ...

A 29 year old gentleman presented to Urology with scrotal pain. He had renal calculi but examination also revealed small testicles for which he was referred to Endocrinology. He achieved normal developmental milestones. He had no history of mumps or testicular torsion or surgery. He had no history of hypospadias or undescended testicles. He was not on any regular medication and denied anabolic steroids use. He reported a normal sense of smell. His body weight was 72 Kg with he...

44 years old lady was referred to Endocrinology Clinic with history of secondary amenorrhea and hyperprolactinaemia (7800), that responded to Cabergolin treatment, which was discontinued after 2 months due to side effects (headaches). There was no galactorrhea or visual field defects. MRI Pituitary initially reported as Empty Sella. Her prolactin levels rose further along with headach after she discontinued Cabergoline (and refused alternatives). She eventually agreed for nigh...